Coming off a surprising run to the AFC Championship Game, the open their 2020 campaign in prime-time, as they travel to Empower Field at Mile High to take on the in the second half of a Monday Night Football doubleheader. This 10:20 p.m. ET kickoff is the final game on the Week 1 NFL schedule. Denver is dealing with significant injuries, with elite edge rusher (ankle) out and top receiver Courtland Sutton (shoulder) listed as questionable.Tenne see is a three-point favorite in the latest Titans vs. Broncos odds from William Hill after opening as a two-point underdog, while Charone Peake Jersey the over-under is 41 after briefly falling as low as 40.5. Before locking in any Broncos vs. Titans picks, make sure you .The SportsLine Projection Model, which simulates every NFL game 10,000 times, is up over $7,000 for $100 players on its top-rated NFL picks since its inception five years ago. It also enters the 2020 NFL season on an incredible 96-65 roll on top-rated NFL picks that dates back to the 2017 season.The model ranked in the Top 10 on NFLPickWatch in three of the past four years on straight-up and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is Eddy Pineiro Jersey way up.Now, the model has set its sights on . You can . Here are the from William Hill and trends for Titans vs. Broncos:Broncos vs. Titans spread: Titans -3Broncos vs. Titans over-under: 41 pointsBroncos vs. Titans money line: Titans -160, Broncos +140TEN: LB led the Titans with a career-high nine sacks last seasonDEN: S led the Broncos with four interceptions and 15 pa s breakupsWhy the Titans can coverBattling the elevation in Denver is always a Justin Moore Jersey challenge for visiting teams, but that home-field edge is mitigated by the fact that there will be no fans permitted at this opener. That should help Tenne see's offense operate at a high level as it looks to build on an extremely strong end to last season.After taking over for ineffective starter early last season, quarterback returns for the Titans and will look to build off a career-best 70.3 completion percentage.Running back bulldozed opposing defenses last season on his way to the league rushing crown with 1,540 yards. Defensively, the Titans received a major boost last week with the signing of edge rusher . He reunites with Titans head coach Mike Vrabel, his former coordinator in Houston, who helped him to a career-best 9.5 sacks in 2017.Why the Broncos can coverDenver will feature a one-two punch at running back with and Alabama Crimson Tide Jersey Sale . Gordon rushed for 612 yards for the last season, while Lindsay led the Broncos with 1,011 yards on 224 carries (4.5 average) and seven touchdowns while playing in all 16 games.Lindsay became the first player since 1967 to rush for 1,000-plus yards in his first two seasons. Plus, he rushed for a touchdown in last season's meeting against the Titans.How to make Broncos vs. Titans picksSportsLine's model is Jordan Harris Jersey leaning under on the total. In fact, it says Tannehill will pa s for 200 yards and a score, while the Broncos' rushing attack will be held to under 100 yards and one TD. It also says one side of the spread hits in well over 50 percent of simulations..So who wins Titans vs. Broncos on Monday Night Football? And which side of the spread cashes well over 50 percent of the time? , and find out.